Priligy - Premature Ejaculation PIll (dapoxetine)

Priligy (dapoxetine) for Premature Ejaculation


Priligy™ is the brand name for dapoxetine (also known as dapoxetine hydrochloride, dapoxetine HCl, and Ambliss).

It’s a new prescription drug for premature ejaculation. It’s a special king of fast reacting SSRI drug, but it’s not an antidepressant.

Dapoxetine is actually the only medication officially approved to treat specifically premature ejaculation treatment.

In February 2009, it was approved for use in Finland and Sweden. Shortly after, approval in Portugal, Austria and Germany followed.

As of this moment it is awaiting approval in other European countries. Filings for approval have been also submitted in Canada, Australia, Mexico, Turkey and six other countries.

However, dapoxetine is still not approved in United States. Initially, it was submitted in December 2004 but FDA (Food and Drug Administration) rejected it in October 2005.

Johnson & Johnson said they’re working to answer questions raised by FDA and continued the development of drug. Two further clinical trials completed in 2006, but dapoxetine has not been approved yet by FDA. Currently it’s in the Phase III of the FDA approval process.

Dapoxetine will be marketed by Janssen-Cilag (part of the Johnson & Johnson family of companies). It is expected to be available for purchase (in countries where it’s approved) around April 2009, and it will require a prescription.

Janssen-Cilag will provide official confirmation of the exact date of product availability in each individual country.

Pfizer (another pharmaceutical giant) is also developing its own version of dapoxetine.

Anyway, how does Priligy™ (dapoxetine) works, and what exactly can you expect from it?

Priligy™ (dapoxetine) belongs to the family of SSRI drugs. What sets it apart is that it was designed specifically for premature ejaculation. (Unlike other SSRI drugs like Paxil, Prozac, and Zoloft that were initially designed to treat depression.)

Also, antidepressants (like Paxil, Prozac, and Zoloft) are usually taken on a daily basis, and to see improvements you might need to wait 2-4 weeks.

Priligy™ (dapoxetine) works much faster, and you don’t need to take it on a daily basis. It’s taken as need, 1 or 2 hours before having sex. Peak effectiveness is at 1.5 hours after taking the drug.

Preliminary studies show that 30 mg and 60 mg dose, taken 1 or 2 hours before sex, work well, while limiting side effects.

Jon L. Pryor, MD, chairman of urologic surgery at the University of Minnesota, lead a study of dapoxetine effectiveness. The study included more than 2,600 men.

The men who participated took one of two dosed of Priligy™ (dapoxetine) or a placebo pill, 1-3 hours before sex.

With their partners, they used a stopwatch to measure their IETL (intravaginal ejaculatory latency time). IETL is the time that elapses from the beginning of penetration to ejaculation. It’s how much you can last.

Before taking Priligy™ (dapoxetine) those 2,600 men could last 54 to 55 seconds, on average.

Let’s take a look at the results of study.

Here’s how long men lasted after taking the pills…

  • 1 minute and 45 seconds (men who took the placebo “dummy” pill)
  • 2 minute and 47 seconds (men who took the 30 mg dose)
  • 3 minutes and 19 seconds (men who took the 60 mg dose)

Men were also asked to rate how well they thought they were able to control their ejaculation. Fair, or fair-or-better control was reported as following…

  • 3% before the study (fair control)
  • 26.4 % of men who took placebo reported fair control
  • 51.8 % of men who took 30 mg dose reported fair-or-better control
  • 58.4 % of men who took 60 mg dose reported fair-or-better control

Pryor’s team also asked the men and their partners about their sexual satisfaction. The “good to very good” sexual satisfaction was reported as following…

  • 20% – 25% before the treatment
  • 25% in the placebo group
  • 39% in the 30 mg dose group
  • 47% in the 60 mg dose group

The study also looked at the Priligy™ (dapoxetine) side effects…

  • Nausea in 8.7 % of men getting 30 mg dose, and 20.1% of men getting 60 mg dose
  • Headache in 5.9% of men getting 30 mg dose, and 6.8% of men getting 60 mg dose
  • Diarrhea in 6.8% of men getting 60 mg dose
  • Dizziness in 6.2% of men getting 60 mg dose
  • 10% of men taking 60 mg dose, and 4% of men taking 30 mg dose quit the treatment because of side effects they experienced.

Priligy™ (dapoxetine) must be prescribed by your doctor. Nevertheless, some online pharmacies already (illegally) sell generic dapoxetine without prescription. I strongly advise not to use dapoxetine without medical supervision.

It comes in a form of tablets, and it’s taken by mouth.

Some general precautions include…

  • Preliminary studies show that taking dapoxetine with PDE-5 Inhibitors (specifically Viagra and Cialis ) is safe and effective. However, you should discuss with your doctor or pharmacist before mixing any prescription medications.
  • Preliminary studies also show that you can drink alcohol when you take dapoxetine. It is safe and it doesn’t impair the drugs effectiveness. However, excessive drinking can cause sexual dysfunction.

Here’s one interesting detail about Priligy™ (dapoxetine)…

Dapoxetine is also known as Ambliss. I found out about this alternative brand name in 2007 at www.amblissfaq.com. The website says Ambliss is registered trademark of Johnson & Johnson.

I’m not sure if Ambliss was initial brand name Johnson & Johnson intended to use for dapoxetine that they discontinued by now – or they still intend to use it along with the new name – Priligy.

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3 comments

How much. Time dapoxtine take for PE

by rj on October 30, 2015 at 8:33 am. Reply #

When is the best time to perform sex’ once u take prilgy tablet

by Vinne on November 20, 2016 at 10:41 am. Reply #

Most help articles on the web are inaccurate or inneeorhct. Not this!

by Vicki on January 5, 2017 at 3:37 pm. Reply #

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