Paxil for premature ejaculation

How To Use Paxil for Premature Ejaculation

Here’s what you need to know about using Paxil for premature ejaculation… 

Paxil is the brand name for paroxetine. It’s a strong SSRI antidepressants that some doctors prescribe for premature ejaculation.

Like other SSRI antidepressants, it works by adjusting the levels of serotonin in the brain. Serotonin is a chemical that carries messages between brain cells.

In men who suffer from premature ejaculation, the serotonin seems to be less active in the section of the brain that controls the ejaculation. Paxil increases the levels of serotonin, and enables you to delay your ejaculation and last longer.

Paxil is legally available only by prescription, but some online pharmacies sell it without prescription. It comes in a form of tablet and is taken orally, preferably in the morning.

You’ll probably first try to use it as needed, 2-12 hours before sex. If that fails, than you’ll use it on a daily basis.

Within first 10 days of use, the concentration of drug in your blood will reach a constant level. However, you mat need to wait 2 to 4 weeks before you see improvement in your ejaculation control.

Starting dose is usually 20 mg per day. But, if needed, your doctor may gradually increase the dose to a daily maximum of 40 mg.

If there’s no improvement within 6 weeks of treatment, or if you experience a lot of negative side effects, your doctor will probably end the treatment.

If Paxil doesn’t help you, you doctor may prescribe you another SSRI antidepressant, to try again. For example, Zoloft or Prozac. If the second SSRI fails to help, then trying the third one probably won’t help.

For more information on using Prozac and Zoloft for premature ejaculation see “How to use Prozac for premature ejaculation” and  “How to use Zoloft for premature ejaculation“.

If that happens, your doctor still can prescribe you another type of antidepressant called the tricyclic antidepressant. A good example of this type of antidepressant is Anafranil.

Researchers have found that Anafranil works better for premature ejaculation than many SSRI antidepressants. However, that comes at a price because Anafranil usually has more side effects than SSRIs.

We’ll talk about Anafranil in detail later.

You should not use Paxil without medical supervision. This is especially true if you are already taking some medications (or have recently do so), or if you have some health issues.

Here are some general warnings and precautions when using Paxil for premature ejaculation

Use it with caution if you….

  • have problems with liver or kidneys
  • have a history of seizure disorders
  • have or had manic-depressive disorder

You should not use alcohol while you’re taking Paxil.

Paxil can cause problems if used along with some other medications such as…

  • Lanoxin, Lanoxicaps (digoxin), a drug used to treat hearth problems
  • Tagamet (cimetidine), a drug for treating stomach acid
  • certain type of antidepressants (MAOIs)
  • Coumadin (warfarin), a prescription drug used to treat or prevent blood clots
  • tryptophan

Also, pregnant and nursing women should not use Paxil. I kinda doubt you’re gonna get pregnant and start breast-feeding babies around… but I had to warn you anyway.

Remember the serotonin? A chemical in the brain that controls your ejaculation? Well, the serotonine is produced in brain from another chemical called the tryptophan. And the tryptophan comes in the brain from foods high in protein such as turkey and milk (and other meat and dairy products).

That’s why you have to be very careful about your diet.

While taking Paxil you may experience some negative side effects. This includes dizziness, tremor, nervousness, insomnia, dry mouth, nausea, constipation, diarrhea, decreased appetite.

It happens rarely, but you could also experience some dizziness upon rising from a seated or prone position, anxiety, urinary disorders, skin rashes, and muscle weakness.

Here’s the full-blown medical description of Paxil. If it all sound Greek to you, don’t worry. This is written by a doctor, for doctors. But I thought you might want to take a look at it. So…

Here it is…


Drug Name
Paroxetine (Paxil) — Potent SSRI antidepressant used to treat premature ejaculation. Improvement may not be evident until at least 3 wk following initiation of treatment. If no benefit (with respect to premature ejaculation) after 6 wk or adverse effects become troublesome, medication should be discontinued in favor of an alternative treatment.

Adult Dose
20 mg PO 2-12 h before sexual relations; alternatively, 20 mg/d PO, gradually titrate to response; not to exceed 40 mg/d

Pediatric Dose
Not established

Documented hypersensitivity; concomitant MAOIs or use within 14 d

B – Usually safe but benefits must outweigh the risks.

Caution in recent MI or unstable heart disease; hyponatremia; although minimal adverse anticholinergic effects (compared with TCAs), use with caution in glaucoma, bladder outlet obstruction, chronic constipation, and other conditions in which adverse anticholinergic effects may exacerbate symptoms; also caution in moderate-to-severe renal or hepatic impairment, because of excessive blood level accumulation (adjust dose accordingly); does not impair motor or cognitive ability with respect to performance of complex tasks, nor does it cause somnolence, but any drug affecting the CNS may cause drowsiness, and driving and performance of other tasks requiring alertness and concentration should be avoided; seizures are rare; caution in preexisting seizure disorder; when used for premature ejaculation (off-label), patients with clinical depression should be treated by a mental health care professional; potential for depressed patients to commit suicide; priapism has been (rarely) reported

Copyright © WebMD, By Mark Jeffrey Noble, MD, Urologic Institute, Cleveland Clinic Foundation, Retrieved from:

If you’re thinking about using Paxil for premature ejaculation, don’t do it without medical supervision. There’s a reason why it’s a prescription-only drug.

Read this:


[…]  ”How To Use Paxil for Premature Ejaculation“,  and “How To Use Prozac for Premature […]

by How To Use Zoloft For Premature Ejaculation on February 22, 2012 at 10:57 am. Reply #

[…] How To Use Paxil for Premature Ejaculation  […]

by How To Use Anafranil for Premature Ejaculation on February 22, 2012 at 11:02 am. Reply #

[…] Paxil  for premature ejaculation […]

by DON'T Take Any Premature Ejaculation Pills Until You See This! on February 22, 2012 at 11:25 am. Reply #

Someone in my Human Sexuality Course asked the same question. The thceaer said it’s actually better for your sexual future if you DO masturbate for the following reasons:1.It exercises the blood vessels that bring blood to the penis for an erection.2. It teaches you how to hold it in when you are with a woman 3. It will actually make your sex life better in the future

by Gustavo on June 1, 2012 at 9:54 pm. Reply #

You have to train yourself not too You can do this tughorh masturbation, by going almost to finish, then stopping for a while, then continuing My GF and I share a BF, and in order to be able to satisfy us both, we worked with him until he would only finish with oral sex ..this is the same basic method male porn stars use except they train themselves to only finish with their hand ..

by Lisandro on June 2, 2012 at 8:35 am. Reply #

A warning that is often not mentioned prior to the suggestion of paxil is that there are terrible withdrawal effects should one decide to stop taking the drug. The extent of this withdrawal depends on the dosage, frequency of administration, and duration of treatment, amongst other things.

I feel that this is something that has to be discussed with someone who is considering the drug, as the withdrawal effects can be severe and can significantly affect the quality of an individual’s life. Furthermore, research on paxil (paroxetine) has found that amongst the SSRI class, this drug displays the longest withdrawal effects amongst all the SSRI’s, with symptoms persisting up to 18 months after cessation.

A factor often overlooked when Dr’s prescribe these drugs

by Mo on May 2, 2013 at 12:12 pm. Reply #

can this drug be taken by ladies?

by amanda on January 3, 2017 at 8:56 pm. Reply #

Dear.. any one to guide… One tablet daily for how much time and then how to reduce and at last how to quit????

by Sami on April 25, 2017 at 8:13 pm. Reply #

I take 40mg paxil 6 hours before sex. It works wonders. I only take it before sex. The next day I feel real chill and not very social. Thats my only side effect. If you take it everyday the side effects will probably be more noticeable.

by wes on June 15, 2017 at 10:06 pm. Reply #

not necessarily as you body gets used to it.

by jordan on September 28, 2017 at 1:51 am. Reply #

Pls how can I get this ?

by Gaba on July 27, 2017 at 7:18 am. Reply #

yes it is prescribed for ladies as it’s a standard ssri anti-depressant. only available with a prescription

by jordan on September 28, 2017 at 1:50 am. Reply #

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